As a young lad, analytical chemistry was my jam. I liked big cool machines with lasers and flames. I liked dissolving things in acid. I liked anything that gave off a swirly gas when heated.

For that reason, I have a special empathy for the plaintiffs in Harmony Biosciences, LLC v. Lupin Ltd., C.A. No. 23-1286-JLH-SRF (D. Del. Oct. 27, 2025), and their poor, overworked experts.
The patent there was for a specific crystalline form of a drug. Typically, you would figure out this form via X-ray diffraction (XRD), which involves shooting X-rays at a crystal (typically powdered) from different angles. Via science too involved to get into here, you get a series …







